Project Details
The Irani lab broadly studies molecular mechanisms regulating vascular function in health and disease. We are currently examining the role of dynamic protein lysine acetylation in the regulation of vascular endothelial function, and how microRNAs expressed in the vascular wall protect against or promote vascular disease. We are working toward identifying novel mechanisms that contribute to vascular health and disease in response to changes in the gut microbiome. We are also collaboratively looking at the role protein lysine acetylation plays in governance of cardiac electrical activity. Finally, we are interested in identifying vasospecific factors that are players in whole body energy utilization and metabolism.

Position Details
We are looking for motivated students who are passionate about science to support a project on microRNAs and cardiovascular diseases. The selected student will help in performing experiments involving cell culture, molecular biology (Western blotting, DNA/RNA extraction, qPCR) and histology (tissue processing, sectioning, staining and imaging) and help maintain an animal work (genotyping, tissues harvest, vascular reactivity). Detailed training and supervision will be provided.

Website

Qualifications

  • Must have the motivation to learn and perform research in biomedical research laboratory
  • Have an interest in molecular mechanism regulating vascular function and diseases
  • Prior experience in research is preferred but not mandatory
  • Be willing to work during the summer break

Time Commitment
Student should be able to commit at least 10 hours per week.

Start Date
Immediate 
Near future

Project Duration 
Ongoing or potential to be a continuous position

Compensation
Volunteer (Optional 0-credit hour course for transcript recognition)
Academic Credit (1-4 semester hours)

How to Apply
Please send an email, including your CV and a brief statement describing your interest in this position to Modar kassan at modar-kassan@uiowa.com.