Project details
The Kang lab, located in Medical Laboratories (ML), has two major research interests: Neuroimmunology and Mucosal Immunology. In Neuroimmunology, we focus on the immunobiology of oligodendrocyte progenitor cells (OPCs) in Multiple Sclerosis by using animal models; we also study the immune function of LRRK2 in the pathogenesis of Parkinson's disease. In Mucosal Immunology, we focus on the role of LRRK2-mediated innate immunity in host defense and intestinal inflammation including inflammasome activation. In addition, we study LKB1-driven gut microbiota dysfunction (dysbiosis) in the pathogenesis of gastrointestinal polyposis and tumorigenesis. To integrate these two research interests, our long-term goal is to understand how gut-brain axis modulates the pathogenesis of neurodegenerative diseases. Our research will open novel avenues for the therapy of related diseases.

Your training/learning experience in the Kang Lab will include (but is not limited to) fundamental cellular and molecular technology in Immunology; Animal model-based in vivo research in autoimmune and auto inflammatory diseases; scientific thinking and lab management skills/teamwork. The experience in this lab will prepare you to be an independent/competitive scientists or applicant for higher level education such as Master's or PhD programs.

Qualifications
A strong interest in immunology or molecular biology is required. Applicants should be independent and scrupulous, with strong organizational skills and good habits to write records. Preference will eb given to applicants who are motivated to pursue a career in health science or biomedicine.

Time Commitment
Students must be available for 10+ hours per week in blocks of time that are 4 hours or greater two days a week.

Compensation
Volunteer
Academic Credit

Start Date
Spring semester
Summer semester
Fall semester

Timeline
Ongoing, potential to be a continuous position

How to apply
If interested, please email Zizhen Kang (zizhen-kang@uiowa.edu) with your resume/CV and a brief statement of why you're interested in our lab. Please list relevant courses taken and grades.